|Fasting or Non-fasting||Fasting. You should fast 9–12 hours before taking this test.|
|Turnaround Time for Results|
The APO B/A-1 ratio test is done by measuring the levels of two cholesterol-associated proteins called apolipoprotein B and A-1 in the blood. APO B is present in the low density lipoprotein (LDL) or “bad” cholesterol and APO A-1 is present in the high density lipoprotein (HDL) or “good” cholesterol. The APO B/A-1 ratio test is often done to assess the relative risk of atherosclerosis.
The APO B/A-1 test is a simple blood test collected via venipuncture. The results are reported as a ratio. A low ratio indicates lower risk of atherosclerosis.
APO B/A-1 ratio results:
- 1/2 Average risk: 0.3–0.4
- Twice Average risk: 0.9–1.0
- Three times Average risk: 1.5–1.6
Am I required to fast for this test?
Yes, you should fast 9–12 hours before taking this test.
What are normal levels?
The target APO B/A-1 ratio is 0.4 for men and 0.3 for women. APO B levels below 100 mg/dL and APO A-1 levels above 120 mg/dL are considered normal.1,2,3 The normal values can vary depending on the laboratory. The exact range will be indicated on your report.
What might abnormal levels indicate?
A higher APO B/A-1 ratio indicates a higher risk of atherosclerosis and heart disease. You have 2-fold the average risk if your ratio is 1.0 (for men) or 0.9 (for women), and you have 3-fold the average risk if your ratio is 1.6 (for men) or 1.5 (for women).
Why do I need it?
You may consider taking the APO B/A-1 ratio test to assess your risk of heart disease.
What type of doctor should I see if results are abnormal?
See your primary health care provider who may refer you to a specialist, such as a cardiologist.