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The beta-2 microglobulin (B2M or beta-2-M) test measures the amount of beta-2 microglobulin in the urine. Beta-2 microglobulin is a membrane protein found in all nucleated cells of the body. Elevated beta-2 microglobulin levels in the urine may be a sign of kidney disease.
You will need to provide a urine sample for the beta-2 microglobulin test. The levels are reported as micrograms per milliliter (mcg/mL). Typical beta-2 microglobulin levels in urine range between 0 and 0.3 mcg/mL.
Elevated beta-2 microglobulin levels in urine can result from:
- Kidney disease or disorder
Am I required to fast for this test?
No, you do not need to fast for this test. However, if you are concurrently having another test done that requires fasting, you need to fast for that test as indicated.
What are normal levels?
The normal beta-2 microglobulin levels in urine range from 0 to 0.3 mcg/mL. The normal values can vary depending on the laboratory. The exact range will be indicated on your report.
What are abnormal levels?
Elevated beta-2 microglobulin levels may indicate a kidney disorder.
Why do I need it?
If you have signs or symptoms of kidney disorder, you may consider taking this test.
What type of doctor should I see if results are abnormal?
See your primary health care provider who may refer you to a specialist, such as a nephrologist.